Study on Association of Serum Magnesium Level with Preterm Labour

Abstract

Introduction: Pregnancy portrays a crucial time when a woman can be reached under a diversity of mechanisms with interventions aimed at lessening her risk of preterm birth. The long-term concerns of a premature birth bear behind both economic and social problems Preterm labour may be due to amendments in basic biochemical functions of the body at the cellular level. Aim of the study: The study aims to investigate the association of serum magnesium levels with preterm labour. Methods: An observational cross-sectional study was carried out in the Department of Obs & Gynae, BSMMU Hospital from March 2013 to August 2013. A total of 30 patients (N=30) were enrolled in this study following the inclusive criteria. Data were collected using the predesigned semi-structured questionnaire. Verbal consent was taken before recruiting the study population. Completed data forms were reviewed, edited, and processed for computer data entry. The data analysis was performed using Statistical Package for the Social Sciences (SPSS) Version 25.0. Result: Among the study population (N=30), the mean age was 26.03(±5.37) years and the minimum age was minimum age was19 and the maximum age was 35 years, around two-fifth of the study population completed SSC, ten patients completed HSC and 8 patients were graduated. The mean serum magnesium (mg/dl) level was 1.70±SD, around three-fifth of the study population (19,63.3%) magnesium level was < 1.9 and eleven patients (11, 36.7%) magnesium level was ≥ 1.9. (p<0.05) that was statistically significant. The mean magnesium level according to socioeconomic status in the higher class was 1.88±SD, in the middle class was 1.70±SD and in the lower class was 1.61±SD mean magnesium level significantly decreased in the poor class was statistically significant. Conclusion: Serum magnesium levels can be
used as a predicting tool for preterm labour and serum magnesium estimation must be done in cases of pregnancy to prevent preterm labour. To avoid preterm birth in some extent oral supplementation of magnesium can play a crucial role.