Vol. 5 No. 01 (2022)
Original Article

Clinico-pathological features of breast cancer: A Hospital-Based Case-control Study

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Junaidur Rahman
Assistant Professor, Department of Surgery, Mugda Medical College, Dhaka
MD Mosharraf Hossain
Senior Consultant, Department of Surgery, Mugda Medical College Hospital, Dhaka
Mohammad Ali
Assistant professor, Department of surgery, Shahid Syed Nazrul Islam medical College, Kishoreganj

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Background: Breast cancer is the most frequently diagnosed cancer in females. It has a major impact on health of women. According to a World Health Organization [WHO] estimate, more than 1.2 million people are diagnosed with breast cancer worldwide every year. The aim of the study was to evaluate the clinicopathological features of breast cancer patient Methodology: This case control study was conducted in Department of Surgery, Sylhet MAG Osmani Medical College Hospital, Sylhet and Shaheed Shamsuddin Hospital, Sylhet during January 2012 to June 2012. Sixty-five women with breast cancer fulfilling the inclusion and exclusion criteria were taken in case group and age-stratified random sample of 65 women without breast
cancer were taken in control group. Results: The mean age of the patients was 48.9 (SD ±8.7) years in case group and 47.8 (SD ±8.7) years in control group (p>0.05). Breast lump (96.9%) was the most common presentation. Tumour size was between 2.1 to 5 cm in 36 (55.4%) patients, tumour size was >5 cm in 27 (41.5%) patients and tumour size was <2 cm in 2 (3.1%) patients. Lymph node was positive in 17 (26.2%) cases and negative in 48 (73.8%) cases. The most of the cases 50 (76.9%) histological type of the tumour in this study were invasive ductal carcinoma and 9 (13.9%) were ductal carcinoma in situ and rest 6 (9.2%) were invasive lobular carcinoma. Grade-III constituted 30 (46.2%) cases, grade-II in 24 (36.9%) cases and grade-I in 11 (16.9%) cases. Stage-II constituted 27(41.6%) cases, stage-III in 21 (32.3%) cases, stage-IV in 11 (16.9%) cases and stage-I in 6 (9.2%) cases. Conclusion: Most of the patients in our country present with advanced stage of breast cancer, at which time there would metastasis leading to a low survival rate. Early detection and therapeutic advances have been made with considerable improvement in disease-free
and overall survival in breast cancer.


Published 14-11-2022


  • Breast cancer,
  • Clinical presentation,
  • Histology,
  • Staging

How to Cite

Rahman J, Hossain MM, Ali M. Clinico-pathological features of breast cancer: A Hospital-Based Case-control Study. The Insight [Internet]. 2022 Nov. 14 [cited 2023 Feb. 4];5(01):89-100. Available from: https://bdjournals.org/index.php/insight/article/view/212