Bacterial Isolates from Throat and Anterior Nares in Urban, Rural and Slum Areas School Going Children, Rajshahi

Abstract

Introduction: Normal flora is beneficial to the host because they can limit the growth of pathogenic organisms by occupying the receptors on the lining surfaces and production of the antimicrobial substance. Reduction in populations of normal flora can promote opportunistic infection. This study aimed to determine the bacterial isolate from the throat and anterior nares of school-going children. Methodology: This observational type of cross-sectional study was conducted at the Department of Microbiology of Rajshahi Medical College, Rajshahi, and in the schools of urban, rural, and slum areas in and around Rajshahi city. Bangladesh. The study took place from January 2012 to December 2012. Throat swabs and nasal swabs were taken from six schools (Two urban, two rural, and Two slum areas) and 50 pairs of samples from each school were collected. Muller Hinton agar plates were used for drug sensitivity test and in the case ofStreptococcus pyogenes and Streptococcus pneumoniae Muller Hinton agar with 5% sheep blood were used. All Data were analyzed by SPSS version 22. Results:The throat and anterior nares of the study population in three age groups in six different schools. The highest number of pathogens in both samples of school-going children in the age group of 06 to 08 years are found in 41(46.59%) and 36(40.9 1) cases followed by the age group >08 to 10 years are 32(34.41) and 29(31.18%) cases, the lowest number in the age group >10-12 years 24(20.17) and 21(17.65) cases respectively. In all age groups colonization in the throat is found more than anterior flares.Among them, MRSA was 14 (12.61%) with an individual sample in the throat and anterior nares, 03 (12%), and 14(12.79).Conclusion:This study concluded that throat and nasal colonization by potentially pathogenic bacteria are significant in this region. A huge number of school-going children from different areas (urban, rural, and slum) and both sexes are colonized with pathogenic bacteria of respiratory tract infections. Among these areas, colonization is most common in children of slum areas followed by rural and urban. Acute respiratory tract infection is the leading cause of morbidity and mortality in both developing and developed countries.