Assessment of Serum Uric Acid in Hypertensive Patients

Abstract

Introduction: Hypertension is a global health issue, impacting over 1.13 billion people and increasing risks of cardiovascular disease, stroke, and kidney failure. Defined by blood pressure readings over 130/80 mmHg, it is primarily essential hypertension with no specific cause. Untreated can increase serum uric acid (SUA) levels due to decreased renal blood flow. Hyperuricemia, often from under-excretion, contributes to hypertension, chronic kidney disease, and heart disease. Aim of the study: The study aims to assess the serum uric acid levels in essential hypertension and its correlation with the severity and known duration of hypertension. Methods & Materials: This observational study was conducted at Dhaka Medical College's Nephrology Department over 18 months to investigate essential hypertension in 58 patients. Participants were selected based on specific inclusion and exclusion criteria, excluding those under 18, diabetic patients, and those with specific medical histories.. Result: The study population consisted of 58 participants, predominantly aged 41-50 (37.93%), with a mean±SD age of 52.2±11.8 years. There were more males (65.52%) than females (34.48%), indicating a higher prevalence of hypertension in males. Most participants had a BMI of 18.5-24.9 kg/m² (56.90%), with a mean BMI of 28.0±3.6 kg/m². The average systolic and diastolic blood pressures were 154.91±10.07 mmHg and 93.19±7.24 mmHg, respectively.. Conclusion: The study finds a strong link between serum uric acid levels and hypertension severity in patients. Higher uric acid levels correlate with more severe hypertension, emphasizing the importance of regular monitoring and treatment. Addressing hyperuricemia could improve blood pressure control and reduce cardiovascular risks in hypertensive patients.