Vol. 6 No. 01 (2023)
Original Article

Frequency of Patent Ductus Arteriosus in Children with Congenital Rubella Syndrome — A Study in a Tertiary Care Hospital

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Md Ashfaque Ahemmed Khan
Classified Child Specialist & Interventional Paediatric Cardiologist, Department of Paediatric Cardiology, Combined Military Hospital, Dhaka, Bangladesh
Mohammad Nazmul Islam Bhuiyan
Classified Child Specialist & Interventional Paediatric Cardiologist
Nurun Nahar Fatema
Paediatric & Structural Interventional Cardiologist
Md Ferdousur Rahman Sarkar
Classified Child Specialist & Interventional Paediatric Cardiologist, Department of Paediatric Cardiology, Combined Military Hospital, Dhaka, Bangladesh
Sultana Yesmin
Assistant Professor, Department of Pharmacology, Dhaka Dental College, Dhaka, Bangladesh

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Abstract

Introduction: Congenital Rubella Syndrome (CRS) has long been characterized by the triad of deafness, cataracts, and cardiovascular malformations (CVMs). The frequency of Patent Ductus Arteriosus (PDA) in children with Congenital Rubella Syndrome (CRS) is a critical topic in pediatric cardiology and infectious disease research. Aim of the study: This study aimed to assess the frequency of Patent Ductus Arteriosus (PDA) among children with Congenital Rubella Syndrome (CRS). Methods and Materials: This cross-sectional observational study was conducted at the Department of Pediatric Cardiology, Combined Military Hospital (CMH), Dhaka, Bangladesh, from June 2020 to June 2021. A purposive sampling technique was adopted. A total of 50 cases with CRS were selected as the study population. Data were collected and processed, and subsequent analysis and reporting were conducted using MS Office tools. Result: Among the total participants, 98% were IgG-positive and 48% were IgM-positive. Out of the 50 study patients, seven cases (14.0%) were diagnosed with pure PDA (Patent Ductus Arteriosus) without any other associated abnormalities. The remaining patients exhibited various combinations of PDA and other cardiac abnormalities. Specifically, thirteen patients (26.0%) were found to have normal cardiac anatomy without any significant abnormalities. Conclusion: Among children with suspected congenital rubella syndrome (CRS), cardiovascular malformations are common. Patent Ductus Arteriosus was found in more than two-thirds of children with congenital heart disease, either occurring in isolation or combination with other congenital heart diseases.

Published 21-01-2024

Keywords

  • Rubella,
  • Patent Ductus Arteriosus,
  • IgG,
  • IgM,
  • Congenital Rubella Syndrome

How to Cite

1.
Khan MAA, Bhuiyan MNI, Fatema NN, Sarkar MFR, Yesmin S. Frequency of Patent Ductus Arteriosus in Children with Congenital Rubella Syndrome — A Study in a Tertiary Care Hospital . The Insight [Internet]. 2024 Jan. 21 [cited 2024 Apr. 23];6(01):138-43. Available from: https://bdjournals.org/index.php/insight/article/view/347