Clinical aspects and microbiological pattern of diabetic foot in surgical practice: A study in a tertiary academic hospital, Bangladesh

Abstract

Background: We have very few authentic data regarding the microbiological pattern of diabetic foot in our surgical practice so far. With this in mind, a prospective study was conducted in BIRDEM General Hospital, Bangladesh in the recent past. This study encouraged us to conduct a similar study in Khulna Medical College hospital, Bangladesh. Objective: This study was conducted to assess the microbial pattern, antibiotic sensitivity and other clinical aspects of diabetic foot in our setup. Methodology: This study was a prospected study in Dept. of Surgery, Khulna Medical College Hospital, Bangladesh from January 2018 to July 2021. A total 120 patients with diabetic foot were included on the basis of convenient sampling. Result: Most of the patients with diabetic foot were female (63.3%). The incidence was associated with age of the patients. Using the Wagner ulcer grading system, it was found that most of the diabetic foots were in grade III (35.0%). Most the infection was polymicrobial (82.5%) and frequently isolated micro-organisms were Pseudomonas (29.3%) and Streptococcus (26.7%). The antibiotics sensitivity against the micro-organisms suggest that the usual sensitive antibiotic were Colostin (93.3%), Imipenem (83.3%%) and Meropenem (80.8%). The rate of amputation was approximately 25%. Conclusion: Advanced age is an associated factor for diabetic foot. Incidence is higher in female. Grade IV ulcer is most common. Infection is most often polymicrobial. Pseudomonas and Streptococcus was frequently observed organism which are best sensitive to Colostin, Imipenem and Meropenem. The overall amputation rate is 25%.