Observational Analysis of Psoriatic Arthritis: Comorbidities and Patient Characteristics in 100 Cases

Open Access

Abstract

Background: Psoriatic arthritis (PsA) is a chronic inflammatory musculoskeletal disease associated with psoriasis, characterized by heterogeneous clinical features and frequent systemic co-morbidities. Objective: To evaluate the clinical characteristics and co-morbidities among 100 patients with PsA. Methods & Materials: A cross-sectional observational study was conducted on 100 patients fulfilling the CASPAR criteria for PsA. Demographic data, clinical subtypes, disease duration, laboratory markers, and associated co-morbidities were recorded. Statistical analysis was performed using descriptive statistics. Results: Among 100 patients, 58 were male and 42 female (M:F=1.4:1), with mean age 43.8±12.4 years. The most common subtype was oligoarticular (36%), followed by polyarticular (30%), spondyloarthritis (18%), distal interphalangeal predominant (10%), and arthritis mutilans (6%). Nail involvement was observed in 64% and enthesitis in 42%. Major co-morbidities included hypertension (38%), diabetes mellitus (28%), dyslipidemia (24%), obesity (22%), ischemic heart disease (12%), and depression/anxiety (18%). Conclusion: PsA shows diverse clinical patterns, with oligoarticular and polyarticular subtypes most prevalent. Co-morbidities, especially metabolic syndrome components, are common, highlighting the need for multidisciplinary management.