Abstract
Background: LVH is a significant risk indicator for cardiovascular issues in hypertension. While ECG is straightforward, low-cost, and easily accessible for screening, echocardiography is more effective at identifying structural LVH. Given the scarce evidence in Bangladesh, this research assessed the association between LVH identified through ECG and echocardiography and the diagnostic efficacy of ECG in patients with hypertension. Methods & Materials: A cross-sectional study of 100 hypertensive patients aged ≥45 years was conducted at Rangpur Medical College and Hospital and the Hypertension and Research Center during 2024-2025. LVH was assessed by 12-lead ECG using the Sokolow-Lyon criterion and echocardiographic LVMI. Data were analyzed using SPSS 25.0, with p<0.05 considered significant. Results: In a group of 100 hypertensive individuals, the average age was 57.3 ± 9.1 years, with 64% being male. The average length of hypertension was 7.87 ± 4.02 years. LVH was identified in 22.0% using ECG and 34.0% using echocardiography. Patients with ECG-confirmed LVH showed significantly elevated IVSd, LVPWd, LV mass, and LVMI (all p<0.001). Sokolow-Lyon voltage displayed notable positive correlations with LV mass (r=0.52), LVMI (r=0.55), IVSd (r=0.43), and LVPWd (r=0.39; all p<0.001). ECG demonstrated 52.9% sensitivity, 93.9% specificity, 81.8% positive predictive value, 79.5% negative predictive value, and 80.0% overall accuracy, exhibiting moderate agreement with echocardiography (κ≈0.50). Conclusion: ECG demonstrated a strong correlation with echocardiographic indicators of LVH and high specificity, although it had restricted sensitivity. Echocardiography identified a higher number of LVH instances and continues to be the preferred method for verifying structural LVH in patients with hypertension.
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