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Keywords
Paediatric Patients
Perioperative Fluid Therapy
Blood Glucose
Ringer's Lactate
Dextrose-Containing Fluids.
Perioperative Fluid Therapy
Blood Glucose
Ringer's Lactate
Dextrose-Containing Fluids.
How to Cite
1.
Perioperative Effects of Dextrose and Non-Dextrose Containing Intravenous Fluids on Blood Glucose Level in Paediatric Patients. Planet (Barisal) [Internet]. 2026 Jun. 19 [cited 2026 Oct. 20];9(04):178-84. Available from: https://bdjournals.org/planet/article/view/1289
Abstract
Background: Perioperative fluid therapy is essential for maintaining blood glucose homeostasis in paediatric patients, but the optimal choice between dextrose-containing and non-dextrose-containing fluids remains controversial due to the risks of both hypoglycaemia and hyperglycaemia. Objective: The aim of the study was to compare the perioperative effects of dextrose-containing versus non-dextrose intravenous fluids on blood glucose levels in paediatric patients. Methods & Materials & Materials: This randomized controlled trial was conducted in the Department of Anaesthesia, Pain, Palliative & Intensive Care in collaboration with the Department of Paediatric Surgery, Dhaka Medical College Hospital (DMCH), Dhaka, Bangladesh (July 2023-June 2024), involving 60 paediatric patients (1-5 years) undergoing elective surgery under general anaesthesia. Patients were randomized to Group A (5% dextrose in 0.225% saline) or Group B (Ringer's lactate) with standardized anaesthesia and fluid management. Capillary blood glucose (T1-T5), haemodynamics, and adverse events were recorded and analyzed using SPSS (p<0.05). Results: In 60 paediatric patients (n=30/group), baseline characteristics, perioperative haemodynamics, blood loss, and fluid volumes were similar between groups (p > 0.05). Blood glucose was significantly higher in the dextrose group from 30 min post-induction to 2 h postoperatively (p = 0.001). Delayed recovery (26.7% vs 6.7%) and hyperglycaemia (36.7% vs 13.3%) were higher in the dextrose group, while severe hyperglycaemia occurred only in this group (10%); hypoglycaemia was comparable (6.7% vs 10%). Conclusion: Non-dextrose-containing intravenous fluids (Ringer's lactate) provide better perioperative glycaemic stability with fewer adverse effects than dextrose-containing fluids in paediatric patients undergoing elective surgery under general anaesthesia.
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