Clinico-Pathological Profile of Thalassemia Patients in A Tertiary Care Hospital

Résumé

Introduction:   Thalassemia is a common hematological disorder in our country having wide spectrum of clinical presentation. The frequency and severity of the several types of thalassemia depend on the racial background of the population. Hb-E Beta thalassemia is prevalent in our country. Objective: To see the clinical features of different types of Thalassemia in northern area of Bangladesh. Methods and Material: Hundred cases were selected from Thalassemia patients admitted in department of pediatrics, from January 2020 to October 2020. A prescribed questionnaire was used to record the information. Necessary physical examination was performed and investigations were done. The data was analyzed by standard procedure. Results:  Out of hundred (100) cases, most (67%) were Hb-E beta Thalassemia, less common (1%) was Hb-E disease, and 1 % case was Hb-E trait. Majority (64%) manifested clinically under one year of age. 53% were male and 47% were female. The major presenting symptom was progressive pallor in 83% cases. Others presenting complaints were low grade fever (45%). Hemoglobin concentration at the time of diagnosis was below 5 gm/dl in 18% patients.