Effects of Insulin in The Last Trimester in Diabetic And Gestational Diabetic Pregnant Women

Abstract

Introduction: Pregnancy is a challenging time for diabetic women due to frequent fluctuations. Insulin plays an important role in the third trimester of pregnancy in diabetic and gestational diabetic women. The study aimed to evaluate the efficacy of insulin in the last trimester in Diabetic and gestational diabetic pregnant women. Methods & Materials: This prospective study was carried out at the Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM), Dhaka, from July 2006 to June 2007with a total of 100 participents. The women were divided into two equal groups. In group A: PGDM (pre-gestational diabetes mellitus) & in group B: GDM (gestational diabetes mellitus). Results: In group A, 40% women belonged to the age group 31-35 years, in group B majority 50% belonged to the age group 20-30 years. The most common complication was PPH, with twelve 24% in group A, and eleven 22.0% in group B. In group A, insulin requirement was 30-75 IU in twenty-seven 54%, <30 IU in fourteen 28%, and >75 IU in nine 18% women, and in group, B was <30 IU in thirty-one 62%, 30-75 IU in fifteen 30% and >75 IU in four 8% women.In both the groups (A and B), the fetal complication was present irrespective of insulin dose. Conclusion: Insulin therapy is an effective method for managing diabetes in pregnant women. It has been found to improve glycemic control, reduce the risk of adverse outcomes, and improve overall maternal and fetal outcomes