Vol. 4 No. 02 (2020)
Original Article

Incidence, Risk Factors and Outcome of Septicemia in Preterm Very Low Birth Weight Neonates in a Tertiary Care Hospital

Swapan Kumar Halder
Assistant Professor, Pediatrics, SBMC, Barishal, Bangladesh
Gias Uddin Ahmed
Assistant Professor, Pediatrics, FMC, Faridpur, Bangladesh
Dipanwita Popy
Lecturer, Community Medicine, SBMC, Barishal
Sabnam Sultana
Junior Consultant, Gynae and Obstetrics, FMC, Faridpur, Bangladesh
Mahbubul Hoque
Associate Professor, Neonatology, BICH, Dhaka, Bangladesh
Most.Nasrin jahan
Assistant professor dept of pharmacology, SBMC, Barishal

Published 20-09-2021

Keywords

  • VLBW,
  • Incidence,
  • Risk factor,
  • Outcome

How to Cite

1.
Incidence, Risk Factors and Outcome of Septicemia in Preterm Very Low Birth Weight Neonates in a Tertiary Care Hospital. Planet (Barisal) [Internet]. 2021 Sep. 20 [cited 2024 Dec. 3];4(02):11. Available from: https://bdjournals.org/index.php/planet/article/view/20

Abstract

Small preterm babies have greater risk of developing illness in the neonatal period than the mature well-grown babies because of immaturity of structures and functions of various organs. The present study was an exploratory prospective cohort study to find out the incidence, the risk factors and outcome of septicemia in preterm VLBW neonates. The incidence of septicemia among the
preterm VLBW neonates was found 62% (57/92). Male sex, delayed admission (>24 hours) in hospital, gestational age (<29.3 weeks), birth weight (<1265grams), rural residence and obstetrical problems (APH, PROM) were found to be associated with increased risk of developing septicemia in preterm VLBW neonates but income status, maternal illness (HTN, DM, Fever), mode
of delivery (NVD, CS) and place of delivery (Home, Hospital) were not associated with increased risk. The mean duration of hospital stay of the septic preterm VLBW neonates were 13.57± 5.39days but non septic cases it was 10.88±4.02 days. Sixty (65.3%) preterm VLBW neonates were improved and discharged with advice from hospital, 3(3.3%) took DORB and unfortunately 29(32.4%) expired

References

  1. Eric C, Eichenwald MD, Ann R, Stark MD. Management and outcomes of very low birth weight. The New England Journal of Medicine 2008;358(16):1700-11.
  2. UNICEF. The State of The World’s Children 2008. UNICEF, New York; December 2007. p118.
  3. Mitra and Associates. National Institute of Population Research and Training (NIPORT), Dhaka, Bangladesh. Bangladesh Demographic And Health
  4. Survey 2007, PRELIMINARY REPORT. MEASURE DHS, Macro International Inc. Calverton, Maryland, USA; December 2007.p.25.
  5. Kabir ARML, Kawsar CA, Sahidullah M, Hassan MQ, Talukder MQK. Situation analysis of child health in Bangladesh, 1994. Bangladesh J Child Health
  6. ;19(2):53-60.
  7. Poundle P, Budhathoki S, Srivastava MK. Maternal risk factors and morbidity pattern of very low birth weight infants: A NICU based study at eastern Nepal. J Nepal Pediatr Soc 2008;29(2):59-66.
  8. Trotman H, Bell Y. Neonatal sepsis in very low birth weight infants at the University hospital of the West Indies. West Indian Med J 2006;55(3):165.
  9. Kate F. Transitional care and the convalescing NICU graduate, in Roberton’s Textbook of Neonatology. 4th ed. China: Elsevier Churchill Livingstone;
  10. p. 385.
  11. Lee SK, Zupancic JAE, Pendray M et al. Transport risk index of physiologic stability: A practical system for assessing infant transport care. J Pediatr 2001;139:220-26.
  12. Gomella TL, Cunningham MD, Eyal FG, Zenk KE. Neonatology: Management, Procedures, On- Call Problems, Diseases, and Drugs. 5th edn. New York: McGraw Hill; 2004. p.77-101.
  13. Islam MN, Khanom S, Kawsar CA. Maternal and socioeconomic risk factors associated with low birth weight. Bangladesh J of Child Health 1995;19(4):112-116.
  14. Ciaravino O, Vigliocco G, Gramajo JH, Sola A. Adolescence, not lack of prenatal care, impacts the incidence and outcome of very low birth weight (VLBW) infants in a developing area. 2. Pediatric Research April 1997; 41(4, Part 2):3.
  15. Banu K, Rahaman S. Disease pattern in neonatal period. Bangladesh J Child Health 1982;6(3/4):129-134.
  16. Nagar A, Chowdhury MK, Kumar P. Small for gestational age babies: Indian scene. Indian J Padiatr 1997;64:221-24.
  17. Stoll BJ, Gordon T, Korones SB, Shankeran S, Tyson JE, Bauer CR et al. Early onset and late onset neonatal sepsis in VLBW neonates: a report from the National Institute of Child Health and Human Development Neonatal Research Network. J Pediatr 1996;129(1):63-80.
  18. Salem SY, Shierner E, Zmora E, Vardi H. Risk factors for early neonatal sepsis. Archives of Gynecology and Obstetrics 2006;274(4):198-202.