Vol. 4 No. 02 (2020)
Original Article

Antibiotic Prophylaxis in Different Surgeries in an Academic Hospital

HTML PDF
  • Zohora Parvin,
  • Kamruddoza Hafizullah,
  • Sultana Yesmin,
  • Hawa Begum,
  • Fatima Jesmin

Published 20-09-2021

Keywords

  • Antimicrobial prophylaxis,
  • Surgery,
  • Surgical wound infection

Copyright (c) 2021 The Planet

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

1.
Antibiotic Prophylaxis in Different Surgeries in an Academic Hospital. Planet (Barisal) [Internet]. 2021 Sep. 20 [cited 2024 Nov. 21];4(02):8. Available from: https://bdjournals.org/index.php/planet/article/view/18

Abstract

The prevention of infection in surgical patients undergoing operation is a major challenge. Inappropriate use of antimicrobials increases the cost thus causing economic burden on the patients which favours the emergence of resistance of bacteria although judicious antibiotic prophylaxis can reduce postoperative wound infections. A prospective study was done in various departments (Surgical allied) of Sher-E- Bangla Medical College Hospital, Barishal from Jan’ 2015 to June’ 2015. The study focused on pattern of prophylactic antibiotics in various surgeries in this hospital. A total one hundred (100) patients undergoing surgery admitted
under various department were included in this study. Pretested proforma including information on patients characteristics, choice of antimicrobials, their route, timing and total duration of prophylaxis were completed. The appropriateness of antimicrobial prophylaxis was assessed as per Standard Guidelines (ASHP, SIGN). The study reveals that third generation
cephalosporin were the most commonly prescribed antibiotic class. Although only 67% of cases required prophylaxis, it was utilized in 82% of procedures, showing unjustifiable in 15% of cases. Mean timing of antibiotic administration was 3.44 ± 1.02 hours before the surgical incision given and the patients were on postoperative antibiotics for a mean duration of 5 days
during their hospital stay. The study found that antibiotic prophylaxis in surgical cases was inappropriate regarding choice of antimicrobials, timing of administration, total duration of administration in most of the cases and it is intended to emphasize on adoption of evidence based guidelines for antimicrobial prophylaxis in surgical treatment.

HTML PDF

References

  1. Chaudhary K Pankaj, Jain Atul, Maurya K Arvind, Gaurav Mishra Ajitesh, Usage of Antimicrobials in Post-operative Patients in a Tertiary Care Teaching
  2. Rural Hospital in India, ejpmr2015,2(4), 328-337.
  3. Martone WJ, Nochols RL. Recognition, prevention, surveillance and management of surgical site infections. Introduction to the problem and
  4. symposium overview. Clin Infect Dis 2001; Suppl33: 67-68.
  5. Haley RW, Culver DH, White JW, Morgan WM, Emori TG. The nationwide nosocomial infection rate: a new need for vital statistics. Am J Epidemiol 1985;
  6. : 159-167.
  7. Centers for Disease Control and Prevention, National Center for Health Statistics Vital and Health Statistics, Detailed diagnoses and procedures national hospital discharge survey 1994. Vol 127. Hyattsville (MD): Department of Health and Human Services; 1997.
  8. Delgado-Rodriguez M, Sillero-Arenas M, Medina-Cuadros M, Martinez-Gallego G. Nosocomial infections in surgical patients: comparison of two measures of intrinsic patient risk.Infect Control Hosp Epidemiol 1997; 18: 19-23.
  9. Horan TC, Culver DH, Gaynes RP, Jarvis WR, Edwards JR,Reid CR. Nosocomial infections in surgical patients in the United States, January 1986-June 1992.
  10. National Nosocomial Infections Surveillance (NNIS) System. Infect Control Hosp Epidemiol 1993; 14: 73-80.
  11. Horan TC, Gaynes RP, Martone WJ, Jarvis WR, Emori TG. CDC definitions of nosocomial surgical site infections, 1992: a modification of CDC definitions
  12. of surgical wound infections. Infect Control Hosp Epidemiol 1992; 13: 606-608.
  13. Horan TC, Emori TG. Definitions of key terms used in the NNIS System. Am J Infect Control 1997; 25: 112-116. 9. Wallace WC, Cinat M, Gornick WB,
  14. Lekawa ME, Wilson SE. Nosocomial infections in the surgical intensive care unit: a difference between trauma and surgical patients. Am Surg 1999; 65:
  15. -990.
  16. Scheel O, Stormark M. National prevalence survey on hospital infections in Norway. J Hosp Infect 1999; 41: 331-335.
  17. McDonald M, Grabsch E, Marshall C, Forbes A. Single-versus multiple-dose antimicrobial prophylaxis for major surgery: a systematic review. Aust N Z J
  18. Surg 1998; 68: 388-396.
  19. Scottish Intercollegiate Guidelines Network. Antibiotic prophylaxis in surgery. Available from URL: http://www.sign. ac.uk/pdf/sign104.pdf [cited
  20. Mar 5].
  21. Dettenkofer M, Forster DH, Ebner W, Gastmeier P, Ruden H, Daschner FD. The practice of perioperative antibiotic prophylaxis in eight German hospitals.
  22. Infection 2002; 30: 164-167.
  23. Kulkarni RA, Kochhar PH, Dargude VA, Rajadhyakshya SS, Thatte UM. Patterns of antimicrobial use by surgeons in India. Ind J Surg 2005; 67: 308-315.
  24. Nichols RL. Preventing surgical site infections: A surgeon’s perspective. Emerg Infect Dis 2001; 7(2): 220–224.
  25. American Society of Health System Pharmacists. The ASHP therapeutic guidelines on antimicrobial prophylaxis in surgery. Available from URL:http://www.ashp.org/DocLibrary/ BestPractices/TG_Surgical.aspx [cited 2009 Mar 11].
  26. Dellinger EP, Hausmann S, Bratzler D et al. Hospitals collaborate to decrease surgical site infections. Am J Surg 2005; 190: 9–15.
  27. Yalcin AN, Serin S, Gurses E, Zencir M. Surgical Antibiotic Prophylaxis in Turkish University Hospital. J Chemother 2002;14: 373-377.
  28. Finkelstein R, Reinhertz G, Embom A. Surveillance of use of antibiotic prophylaxis in surgery. Isr J Med Science 1996; 32: 1093-1097.
  29. T ourmousoglou CE, Yiannakopoulou ECh, Kalapothaki V, Bramis J, St Papadopoulos J. Adherence to guidelines for antibiotic prophylaxis in
  30. general surgery: a critical appraisal. J Antimicrob Chemother. 2008; 61(1):214-218.
  31. Starr MB. Prophylactic antibiotics for ophthalmic surgery. Surv Ophthalmol 1983; 27(6): 353-373.
  32. Munckhof W. Antibiotics for surgical prophylaxis. Aust Prescr 2005; 28: 38-40.23. Kanayama M, Hashimoto T, Shigenobu K, Oha F, Togawa D. Effective prevention of surgical site infection using a Centers for Disease Control and Prevention guideline-based antimicrobial prophylaxis in lumbar spine surgery. J
  33. Neurosurg Spine. 2007; 6(4): 327-329.
  34. Fonseca SN, Kunzle SR, Junqueira MJ, Nascimento RT , de Andrade JI, Levin AS. Implementing 1-dose antibiotic prophylaxis for prevention of surgical
  35. site infection. Arch Surg 2006; 141(11): 1109-1113.
  36. Chen YS, Liv YH, Kunin CM, Huang JK, Tsai CC. Use of prophylactic antibiotics in surgery at a Medical centre in southern Taiwan. J Formos Med Assoc
  37. ; 101: 741-748.
  38. Bratzler DW, Houck PM, Richards C et al. Use of antimicrobial prophylaxis for major surgery: baseline results from the National Surgical Infection Prevention Project. Arch Surg 2005; 140: 174-182.
  39. Vaisbrud V, Raveh D, Schlesinger Y, Yinnon AM. Surveillance of antimicrobial prophylaxis for surgical procedures. Infect Control Hosp Epidemiol 1999; 20(9): 610-613.
  40. Heineck I, Ferreira MBC, Schenkel EP. Prescribing practice for antibiotic prophylaxis for 3 commonly performed surgeries in a teaching hospital in Brazil.
  41. Am J Infect Control 1999; 27: 296-300.
  42. Askarian M, Moravveji AR, Mirkhani H, Namazi S, Weed H. Adherence to American Society of Health-System Pharmacists surgical antibiotic prophylaxis guidelines in Iran. Infect Control Hosp Epidemiol. 2006; 27(8):876-878.
  43. Choi WS, Song JY, Hwang JH, Kim NS, Cheong HJ. Appropriateness of antibiotic prophylaxis for major surgery in Korea. Infect Control Hosp Epidemiol.
  44. ; 28(8): 997- 1002.

Similar Articles

You may also start an advanced similarity search for this article.

About

BD Journals.org is a publishing platform founded by Professor (Dr.) HN Sarker in early 2021. The aim of the publication platform is to promote research in Bangladesh and serves as a media for the dissemination of scientific information and recent knowledge among the readers. Two reputed peer reviewed journals “The Planet”- an official journal of Sher-E-Bangla Medical College, Barishal, Bangladesh and “The Insight”- an official journal of Sheikh Sayera Khatun Medical College, Gopalganj, Bangladesh are now being published in this website.





Important Links

partner