Preeclampsia in Pregnant Women — Association with Disease Severity

Abstract

Introduction: Preeclampsia commonly occurs after 20 weeks of pregnancy in consort with proteinuria and the absence of proteinuria, preeclampsia is known in associated with liver dysfunction, thrombocytopenia, and pulmonary oedema and causes severity, chronic disability, and even death or both mothers and babies. The study aimed to understand the severity of preeclampsia in pregnant women. Methods and materials: An observational case-control study was carried out in the Department of Obstetrics and Gynecology, Sir Salimullah Medical College Mitford Hospital, Dhaka from July 2020 to June 2021. A total number of fifty-six preeclampsia women (N=56) were enrolled in the study. Data were collected using the predesigned semi-structured questionnaire. Verbal & written consent was taken before recruiting the study population. Completed data forms were reviewed, edited, and processed for computer data entry. The data analysis was performed using Statistical Package for the Social Sciences (SPSS) Version 25.0. Result: Respondents' mean age was 27.35 ± 4.85 years. Most of the patients (23,41.1%) completed the primary level, majority of the patients (48,85.7%) were housewives. Respondents' mean systolic blood pressure (SBP) was 164.50 ± 18.13 mmHg and mean diastolic blood pressure (DBP) was 110.82 ± 14.86 mmHg and mean β -hCG concentration was 21301 ± 10102 mIU/ml. Conclusion: This finding suggests that preeclampsia women with severe features have developed levels of serum β-hCG. Maternal complications like eclampsia, PPH, and fetal complications like stillbirth, a higher number of NICU admission, and lower APGAR score were significant in PE with severe features than in PE without severe features and controls.