Effects of Nephrotic Syndrome in Children

Open Access

Abstract

Background: Chronic disorders, particularly nephrotic syndrome, are linked to psychological stress. In children with nephrotic syndrome, glucocorticoid medication can cause a variety of side effects, including behavioral issues. Aim of the study: The purpose of this study was to examine the effects of nephrotic syndrome in children. Methods & Materials: From June 2017 to May 2018, this prospective case control study was conducted at various institutes and medical college hospitals in Dhaka as well as Bogura. This study comprised 100 cases of nephrotic syndrome aged 4-17 years from a purposive sampling approach, as well as 100 age and gender matched control subjects. The behavior of children with nephrotic syndrome was assessed using SDQ grading. A data collecting sheet was created, and the Bengali version of the SDQ format was employed. Variables were measured using various methods. SDQ was compared to these variables, and data were analyzed using SPSS (version 22). Results: The case and control groups had mean ages of 7.86 ± 2.98 and 7.19 ± 2.77 years, respectively. There was no discernible difference in age between the cases and controls. The emotional symptoms scale, conduct difficulties scale, and peer relationship problem were significantly higher in cases than in controls, whereas the pro-social behavior scale was significantly lower. The total SDQ score did not differ significantly between kinds of nephrotic syndromes. However, the IFRNS had a greater SDQ level when compared to the other clinical variants. There was no association between SDQ score and father's or mother's occupation. There was no link between SDQ score and age, disease duration, or monthly household income in patients. Males made up the majority of both categories. Conclusion: This study discovered that children with nephrotic syndrome had much higher levels of emotional symptoms, conduct problems, and peer interaction issues than healthy children, whereas pro-social behavior was significantly lower. Overall, children with nephrotic syndrome had significantly more psychological problems than the control group.