Abstract
Background: Laparoscopic surgery is a minimally invasive approach for procedures like cholecystectomy and hysterectomy, offering less pain, faster recovery, and fewer complications. Anaesthetic challenges from CO₂ pneumoperitoneum exist, but studies show both general and regional anaesthesia are safe, with regional techniques often improving outcomes. This study assessed anaesthetic results and the effect of pneumoperitoneum duration on recovery and complications. Methods & Materials: This observational study involved 110 adults classified as ASA I–III who were scheduled for elective surgical laparoscopy. Intraoperative monitoring along with CO₂ pneumoperitoneum was employed, and patients were categorized based on the duration of pneumoperitoneum (<120 min vs. ≥120 min). Postoperative results encompassed extubation, PACU/hospital duration, pain levels, and complications. Data analysis was conducted with SPSS-27 (p < 0.05). The research received IRB approval and obtained informed consent. Results: In a study of 110 patients (average age 48 years; 80% male), Intraoperative complications were primarily temporary, including hypotension (20%) and hypercapnia (11%). Postoperative recovery was swift (extubation 10.8 min, PACU 69.4 min, hospital 3.6 days), pain reduced from VAS 3.4 to 2.2, and PONV happened in 20.9%. Pneumoperitoneum lasting ≥120 min led to greater hypercapnia, lower blood pressure, longer recovery times, and increased early pain. Conclusion: This study involves ASA I–III patients undergoing laparoscopy, demonstrating that the procedure is safe with mostly temporary complications; however, extended pneumoperitoneum raises risks, necessitating diligent monitoring.

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