Vol. 5 No. 01 (2021)
Original Article

Evaluation of Use Pattern of Analgesics in Post-Operative Pain Management among Surgically Treated Patients in a Tertiary Hospital in Khulna, Bangladesh

Baishakhi Islam
Associate Professor & Head, Department of Pharmacology & Therapeutics, Gazi Medical College, Khulna
Kakali Rani Ghosh
Assistant Professor, Department of Pharmacology & Therapeutics, Khulna Medical College, Khulna
Shamima Akhter
Assistant Professor & Head, Department of Pharmacology & Therapeutics, Khulna Medical College, Khulna
Sifat Jahan Shoshi
Assistant Professor, Department of Pharmacology & Therapeutics, Jessore Medical College, Jessore
Md. Shamsur Rahman
Assistant Professor. Department of Anatomy, Community Based Medical College Bangladesh, Mymensingh
Most. Nasrin Jahan
Assistant professor, Pharmacology, SBMC, Barishal
Pros and Cons of Covid-19 Vaccines – an editorial

Published 20-09-2021

Keywords

  • analgesic,
  • postoperative pain,
  • diclofenac

How to Cite

1.
Evaluation of Use Pattern of Analgesics in Post-Operative Pain Management among Surgically Treated Patients in a Tertiary Hospital in Khulna, Bangladesh. Planet (Barisal) [Internet]. 2021 Sep. 20 [cited 2024 Nov. 25];5(01):7. Available from: https://bdjournals.org/index.php/planet/article/view/12

Abstract

Background: Effective management of postoperative pain provides a significant successful outcome of any surgical cases. Objectives: This study was designed to address the evaluation of using analgesics in relieving postoperative pain. Methods: After taking proper approval from hospital administration a prospective observational study was conducted in 250 surgically treated patients from January 2019 to May 2019 in a tertiary care hospital where patient of all ages and both sexes were included and prescriptions which did not contain analgesics were excluded from the study. Data was collected from day of operation to 5th post- operative day (POD) of each individual patient. Analysis of data was done by SPSS of 18.0 version. Results: Among 250 patients recruited 165 (66%) patients were female and highest numbers of patients were in the age group 18- 37 years 180 (72%). In the day of operation opioid tramadol and non-opioid diclofenac was mostly prescribed analgesic. Associated analgesics
were pethidine and or ketorolac. Among different combinations of analgesics, ketorolac & diclofenac combination 33% is used in highest cases. Average number of analgesic was 2.1 in the day of operation which became 1 in 5th POD. Percentage of patients prescribed analgesics from national essential drug list was 22%. The most common route of administration was intravenous (91.6%). Oral form was prescribed in 4th & 5th postoperative day. Conclusion: These results emphasize that a further study is needed to improve analgesic use by following standard treatment guideline to achieve effective pain management.

References

  1. Garcia JBS, Bonilla P, Kraychete DC, Flores FC, Valtolina EDP, Guerrero C, et al. Optimizing post-operative pain management. Rev Bras Anestesiol.
  2. ;67(4):395-403
  3. Martinez V, Beloeil H, Marret E, Fletcher D, Ravaud P, Trinquart L, et al. Non-opioid analgesics in adults after major surgery : systematic review with network meta-analysis of randomized trials. British Journal of Anaesthesia. 2017; 118(1):22–31.
  4. Woldehaimanot TE, Eshetie TC, Kerie MW. Postoperative Pain Management among Surgically Treated Patients in an Ethiopian Hospital. PLoS ONE. 2014; 9(7):1–9.
  5. Abdullah M, Masud A, Ashrafuzzaman S, Iqbal J. Pattern of use of analgesics in a surgical unit. Bangladesh J Pharmacol. 2009; 4: 21-23.
  6. Malek J, Sevcik P, Bejsovec D, Gabrhelik T, Hnilicova M, Krikava I, et al. Postoperative Pain Management. 2017.
  7. Chou R, Gordon DB, Leon-casasola OA De, Rosenberg JM, Bickler S, Brennan T, et al. Management of Postoperative Pain: A Clinical Practice Guideline From the American Pain Society, the American Society of Regional Anesthesia and Pain Medicine, and the American Society of Anesthesiologists’ Committee on Regional Anesthesia, Executive Committee, and Administrative Council. The Journal of Pain. 2016; 17(2):131–57.
  8. Sen S, Bathini P. Auditing Analgesic Use in Post-operative Setting in a Teaching Hospital. Journal of Clinical and Diagnostic Research. 2015; Vol9(4):10–3.
  9. Glowacki D. Effective Pain Management and Improvements in Patients’Outcomes and Satisfaction. American Association of Critical-Care Nurses.2015; 35(3):33–42.
  10. Khan ZH, Karvandian K, Maghsoudloo M, Albareh HM. The role of opioids and non-opioids in postoperative pain relief; A narrative review.Archives of Anesthesiology and Critical Care. 2018; 4(1): 430-435
  11. Toro MM, John S, Faruqui AR. Pattern of use of analgesics in post-operative pain management in adults undergoing laparotomy surgery : a prospective observational study. International Surgery Journal. 2018 Feb; 5(2):662-667.
  12. Saxena AK, Ramachandran R. Gulati M, Kumar M. Cyclooxygenase -2 inhibitors in postoperative pain and chronic pain management: current
  13. opinions and future perspectives. Indian J. Anaesth. 2005; 49 (3): 170 – 179.
  14. Martínez AG, Rodriguez BE, Roca AP, Ruiz AM. Intravenous Ibuprofen for Treatment of Post- Operative Pain : A Multicenter, Double Blind, PlaceboControlled, Randomized Clinical Trial. PLoS ONE: e0154004.2016; 11(5)1–16.
  15. Rahman S, Begum ZA, Samad K. Prescribing pattern of non-steroidal anti-inflammatory drugs at outpatient departments of teaching
  16. hospitals. Bangladesh J Pharmacol.2007;2:1-6
  17. SN Alam, S Rehman, SMR Zaidi, S Manzar. Audit of general surgical unit: Need for self-evaluation. Pakistan Journal of Surgery. 2007;23(2):141-144
  18. Bhansali NB, Gosai TR, Dholaria NK, Suthar SD, Chacko J, Chavda DA et al. Drug utilization study in postoperative patients in surgical ward of
  19. a tertiary hospital attached with medical college. Der Pharmacia Lettre. 2013;5 (1):251-257.
  20. Vallano A, Malouf J, Payrulet P, Baños JE. Analgesic use and pain in the hospital settings. Eur J Clin Pharmacol. 2007; 63:619–626.
  21. Nasir M, Parveen RA, Alam NN. Pattern of Analgesic Use in PostOperative Pain Management in a Tertiary Level Teaching Hospital in Bangladesh Pattern of Analgesic. Research J. Pharm. and Tech. 2016; 9(5):1-4.