Vol. 7 No. 01 (2023)
Original Article

Serum Magnesium Level in Different Stages of Chronic Kidney Disease Patients in a Tertiary Care Hospital

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Md Rokib Sadi
Resident Physician, Department of Medicine, Rajshahi Medical College Hospital, Rajshahi, Bangladesh
Md Anwarul Amin
Deputy General Manager, ACI Pharmaceuticals Limited, Dhaka, Bangladesh
Md Hasan Ali
Department of Pharmacy, North South University, Dhaka, Bangladesh
Dihan Tahite
Department of Pharmacy, University of Dhaka, Dhaka, Bangladesh
Md Khalilur Rahman
Professor (Retired), Department of Orthopedic Surgery, Tairunnessa Memorial Medical College & Hospital, Gazipur, Dhaka, Bangladesh

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Abstract

Introduction: Chronic Kidney Disease (CKD) is a growing global health concern with complex metabolic implications, including alterations in serum magnesium levels. This study aims to explore the relationship between serum magnesium levels and different stages of CKD, as well as the impact of the duration of illness on this relationship. Methods & materials: This cross-sectional study was conducted on 220 patients admitted to the Department of Nephrology and Medicine, Rajshahi Medical College Hospital, Rajshahi, Bangladesh. Data were collected on demographic variables, CKD stages, and biochemical parameters, including serum magnesium levels. The duration of illness was also recorded and analyzed. Result: The mean age of the study population was 52.89±10.42 years, with a male predominance (63.6%). A high prevalence of advanced CKD stages was observed, with 67.28% of participants in either Stage 4 or Stage 5. A significant negative correlation was found between serum magnesium levels and estimated Glomerular Filtration Rate (eGFR) (r=-0.735, p<0.01). Additionally, a positive association was identified between the duration of illness (12 to 36 months in 65.45% of participants) and advanced CKD stages. Conclusion: The study reveals a complex interplay between serum magnesium levels, eGFR, and the duration of illness in CKD patients. The high prevalence of advanced CKD stages and its association with longer duration of illness underscore the need for timely diagnosis and effective early intervention strategies. Monitoring serum magnesium levels could be instrumental in the comprehensive management of CKD patients.

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Published 10-02-2024

Keywords

  • Chronic,
  • Kidney,
  • Renal,
  • GFR,
  • eGFR

How to Cite

1.
Sadi MR, Amin MA, Ali MH, Tahite D, Rahman MK. Serum Magnesium Level in Different Stages of Chronic Kidney Disease Patients in a Tertiary Care Hospital. Planet (Barisal) [Internet]. 2024 Feb. 10 [cited 2024 Jul. 25];7(01):406-15. Available from: https://bdjournals.org/index.php/planet/article/view/444