Clinical Presentation & Dyslipidemia in Post-Menopausal Women with Acute Myocardial Infarction

Abstract

Introduction: While most CHD risk factors are similar between men and women, they can often vary in strength and association and change throughout their lifetime. This is especially evident for lipids, with low high-density lipoprotein cholesterol (HDL-C) cholesterol and hypertriglyceridemia being stronger predictors of CHD in women than in men. Aim of the study: This study aimed to analyze the clinical presentation and dyslipidemia in post-menopausal women with acute myocardial infarction. Methods and materials: This cross-sectional descriptive study was carried out at the Department of Medicine and Department of Cardiology, Sher-E-Bangla Medical College Hospital, Barisal, Bangladesh, from January 2019 to July 2019. A total of 105 postmenopausal women with acute myocardial infarction (AMI) were selected purposively. Data entry and descriptive analysis were done using SPSS (Statistical Package for Social Science) for Windows version 20.0. Output of data and graphical representation was done using Microsoft Office chart and Microsoft Word. Result: On ECG, arrhythmia was seen in 34.28% of subjects. Ischemia was observed in 30.47% subjects. Old MI (15.23%) was also evident in ECG. A majority (36.19%) of the subjects had <41-50% LV dysfunction. Only 12.38% had ≥56% LV function on echocardiography. The serum cholesterol of the study subjects was ranged. from 112 mg/dl to 325mg/dl. The mean ± SD cholesterol level was 197.8±55.1 mg/dl. Mean (± SD) triglyceride, HDL, and LDL levels were 259.0 (+91.5) mg/dl, 39.2 (±6.6) mg/dl and. 147.5 (+46.45) mg/dl respectively. Dyslipidemia was present in 91(86.67%) subjects. Conclusion: Majority of the post-menopausal women with acute myocardial infarction present with chest pain and dyspnea. They had raised cholesterol and triglyceride levels. This study concludes that post-menopausal women should pay early attention to their abnormal lipid profile to prevent ischemic heart disease.