https://bdjournals.org/index.php/ijmdr <p>International Journal of Medical and Dental Research (IJMDR)is the official journal of the Society of Retired Professors of Medical Science and accepts articles for publication from home and abroad. This is a biannual, peer-reviewed journal and aims to publish work of the highest quality from all branches of medical science. The aim of the publication is to promote research in Bangladesh and serve as a media for the dissemination of scientific information and recent knowledge among readers.</p> <p><strong>ISSN (Print)</strong>: 2959-0159 <strong>ISSN (Online)</strong>: 2959-748X</p> Society of Retired Professors of Medical Science (SRPMS) en-US International Journal of Medical and Dental Research 2959-0159 https://bdjournals.org/index.php/ijmdr/article/view/233 <p><strong><em>Introduction:</em></strong><em> Urinary tract infection is the most common human infection. Resistance of uropathogen to antibiotic is now a global problem. E. coli is the most common organism. Variation in resistance pattern of different antibiotic are known to occur in different geographic areas as well as in the same country. Given this background the aim of this study was to identify common uropathogens and their résistance profile among the patient at the OPD of Sheikh Sayera Khatun Medical College, Gopalganj. <strong>Materials and method</strong>: Appropriate urine specimens of all suspected cases of UTI are processed in the laboratory for detection of significant bacteriuria. Bacterial uropathogens isolated were identified by standard biochemical tests and antibiotic susceptibility test to antibiotics was carried out on them by using Kirby-Bauer disc diffusion technique. <strong>Results: </strong>Among 77 uropathogens, Escherichia coli accounted for 73 (94.80%) of all isolate and others are Pseudomonas 3(3.89%) and Klebsiella (1.29%) respectively. E. coli showed sensitivity to Meropenem-73(100%), netilmycins-71(97.25%), amoxicillin-clavulanic acid-67(91.77%), gentamycin-64(87.66%), nitrofuantoin-63(86.29), levofloxacin-(83.55%) and ceftazidime-59 (80.81%) respectively. In contrast, E. coli. were resistant to Nalidixic acid- 62(84.93%), Cefachlor- 62(84.93%), Cefuroxime- 47(64.38), Cefixime- 45(61.64%) and ciprofloxacin- 34(46.57%). <strong>Conclusion: </strong>Knowledge about uropathogens and local antibiotic resistance is needed to determine the appropriate empirical antibiotic therapy and overcoming drug resistance. </em></p> <p>&nbsp;</p> Rafiuddin Ahmed Lakhsman Chandra Kundu Copyright (c) 2023 International Journal of Medical and Dental Research 2023-02-28 2023-02-28 1 02 4 8